The purpose of this research is to investigate the impact of the physical quality of the work environment on reducing stress in women, and to identify effective factors in improving the quality of the work environment for women in Iran and Turkey. With the increasing presence of women in various social spheres and the multiple responsibilities they undertake, attention to improving their work environment conditions has become particularly important. A suitable work environment not only affects the personal growth of women, but also the creation of quality and aesthetically pleasing work spaces can help reduce stress and increase the efficiency of women. This research uses a descriptive-comparative method to examine stress in women in Iran and Turkey, and data has been collected through field studies, questionnaires, and in-depth interviews with working women in both countries. In addition, the effects of environmental design on the behavior and emotions of women in both countries have been analyzed. The results show that appropriate design and the physical quality of the work environment can significantly affect the reduction of stress in women. Creating safe and beautiful spaces with appropriate functionality not only helps to improve the quality of women's working lives, but also increases their efficiency and productivity. Furthermore, cultural and social differences in both countries are observable in how these factors exert their influence.